Immunotherapy + Immunotherapy
Learn more about how CTLA-4 pathway inhibition enhances antitumor response
PD-L1 blockade also increases the availability of ligands for the co-stimulatory pathway (CD80, CD86) in the lymph node, thereby enhancing T-cell activation and proliferation.
Learn more about PD-L1 pathway inhibition
TAKE A DEEPER LOOKat the science of combination immuno-oncology therapy
Combination strategies are a key area of clinical research because they have the potential to simultaneously inhibit complementary immunosuppressive pathways.
PD-L1=programmed cell death ligand-1; CTLA-4=cytotoxic T-lymphocyte-associated antigen-4.
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